A pharmacology primer : theory, applications, and methods /
Terry Kenakin.
- 2nd ed.
- Amsterdam ; Boston : Academic Press/Elsevier, c2006.
- xviii, 299 p. : ill. (some col.) ; 28 cm.
Includes bibliographical references and index.
What is pharmacology? -- How different tissues process drug response -- Drug-receptor theory -- Pharmacological assay formats : binding -- Agonists : the measurement of affinity and efficacy in functional assays -- Orthosteric drug antagonism -- Allosteric drug antagonism -- The process of drug discovery -- Target- and system-based strategies for drug discovery -- "Hit" to drug : lead optimization -- Statistics and experimental design -- Selected pharmacological methods.