TY - BOOK AU - Kenakin,Terrence P. TI - A pharmacology primer: theory, applications, and methods SN - 9780123705990 AV - RM301.25 .K46 2006 PY - 2006/// CY - Amsterdam, Boston PB - Academic Press/Elsevier KW - Pharmacology, Experimental N1 - Includes bibliographical references and index; What is pharmacology? -- How different tissues process drug response -- Drug-receptor theory -- Pharmacological assay formats : binding -- Agonists : the measurement of affinity and efficacy in functional assays -- Orthosteric drug antagonism -- Allosteric drug antagonism -- The process of drug discovery -- Target- and system-based strategies for drug discovery -- "Hit" to drug : lead optimization -- Statistics and experimental design -- Selected pharmacological methods UR - http://www.loc.gov/catdir/enhancements/fy1007/2010286945-d.html ER -